Decreased NK cell activity after partial vulvectomy in pregnant patient with vulvar intraepithelial neoplasia 3 (VIN3)

Malgorzata Jerzak 1, Andrzej Nowakowski 1, Monika Ohams 2, Andrzej Górski 2, Włodzimierz Baranowsk 1
1 - Department of Gynecology and Gynecological Oncology, Military Institute of Medicine, Warsaw, Poland
2 - Department of Clinical Immunology, Transplantation Institute, University Medical School, Warsaw, Poland
Ann Agric Environ Med

ICID: 1235167
Article type: Original article
 
 
 Abstract
Introduction and objective
. The study presents the problem of immune disturbances in pregnant women with vulvar carcinoma in situ (VIN3).
Material and methods. NK cell and T reg activity in the study patient were analysed using flow cytometry.
Results. Decreased NK cell activity and but increased T reg activity were observed after vulvectomy, with subsequent successful pregnancy outcome.
Conclusions. Although vulvar cancer may influence immune cell activity, this issue merits further study
DOI: 10.5604/12321966.1235167
  FULL TEXT STATS

Recommend this article to:

Name:
E-mail:
From:
Language:


Related articles in IndexCopernicus™
     vulvar cancer [10 related records]
     NK cell [4 related records]
     Pregnancy [16558 related records]
     T reg [0 related records]



 

Related articles

A Lahlou,  Baybay,
 Childhood vitiligo: Clinical epidemiological...
 Objective: To study the clinical and the epidemiologic profiles of childhood vitiligo. Patients and Methods: We prospectively analyzed the clinical data of children with vitiligo presented to the dermatology derpartement at University Hospi...
ABSTRACT
K Korabiusz, A Wawryków,
LYMPHEDEMA DURING PREGNANCY - CASE STUDY...
...
ABSTRACT
C Radia, G Salim,
 Pemphigoid gestationis: A Moroccan study...
 Introduction: Pemphigoid gestationis (PG) is a rare autoimmune skin disorder that occurs during pregnancy. Materials and Methods: Prospective study including all cases of PG diagnosed between 2010 and 2015. Results: We reported 16 patie...
ABSTRACT