Decreased NK cell activity after partial vulvectomy in pregnant patient with vulvar intraepithelial neoplasia 3 (VIN3)

Malgorzata Jerzak 1, Andrzej Nowakowski 1, Monika Ohams 2, Andrzej Górski 2, Włodzimierz Baranowsk 1
1 - Department of Gynecology and Gynecological Oncology, Military Institute of Medicine, Warsaw, Poland
2 - Department of Clinical Immunology, Transplantation Institute, University Medical School, Warsaw, Poland
Ann Agric Environ Med

ICID: 1235167
Article type: Original article
 
 
 Abstract
Introduction and objective
. The study presents the problem of immune disturbances in pregnant women with vulvar carcinoma in situ (VIN3).
Material and methods. NK cell and T reg activity in the study patient were analysed using flow cytometry.
Results. Decreased NK cell activity and but increased T reg activity were observed after vulvectomy, with subsequent successful pregnancy outcome.
Conclusions. Although vulvar cancer may influence immune cell activity, this issue merits further study
DOI: 10.5604/12321966.1235167
  FULL TEXT STATS

Recommend this article to:

Name:
E-mail:
From:
Language:


Related articles in IndexCopernicus™
     vulvar cancer [10 related records]
     NK cell [4 related records]
     Pregnancy [16557 related records]
     T reg [0 related records]



 

Related articles

T Emamgoli Khooshehchin, Z Keshavarz,
Perceived needs in women with gestational diabetes...
INTRODUCTION: Diabetes is the most common medical complication of pregnancy. It can be associated with many complications for mother and fetus. Gestational diabetes is also one of the main health issues in Iran. Therefore, the present study is aimed...
ABSTRACT
E Ağaçayak, B Alan,
Adölesan Gebelerin Maternal ve Fetal Sonuçların...
Amaç: Bu çalışmada amacımız hastanede karşılaştığı­mız adölesan gebeliklerdeki maternal ve fetal sorunlar ile adölesan olmayan gebeliklerde görülen maternal ve fetal sorunları karşılaştırılarak tartışmaktır. Yöntemler: D...
ABSTRACT
M ARABSALMANI, M  BEHZADIFAR,
Is Herpes Simplex virus (HSV) a sign of Encephalit...
 [url=http://journals.sbmu.ac.ir/ijcn/article/view/11309]javascript:void(0);/*1503724482369*/[/url]...
ABSTRACT