Iron status in obese women

Hanna Stankowiak - Kulpa 1, Angelika Kargulewicz 1, Arkadiusz Styszyński 2, Ewelina Swora - Cwynar 1, Marian Grzymisławski 1
1 - Department of Internal Medicine, Metabolism and Dietetics, Poznan University of Medical Sciences, Poland
2 - Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland
Ann Agric Environ Med

ICID: 1232092
Article type: Original article
 
 
Introduction and objective. A decreased concentration of iron, and consecutively haemoglobin, ferritin and decreased level of saturated transferrin, were observed in obese individuals more often than in healthy subjects. The purpose of this study was to determine whether iron, ferritin, transferrin saturation are significantly diminished in obese female patients compared to non-obese counterparts, and whether excess adiposity and inflammation were associated with depleted iron.
Materials and methods. Female patients (n=48) diagnosed with obesity (BMI > 30 kg/m2), aged 18–40 were accepted for the study. A control group (n=30) encompassed normal weight women, aged 18–30. All obese women obtained an individually adjusted dietary plan with an energy content of 1,500 kcal. Blood glucose, insulin, lipids, ferritin, TIBC and iron concentrations were assayed in serum twice, initially and after 8 weeks of dieting.
Results. The obese women at the initial evaluation, in comparison to non-obese control women, were characterized by a significantly lower mean red blood cell volume (MCV; 84.2±12.4 vs. 91.3±9.3 fL; p<0,0001), serum iron level (92.6±42.4 vs. 119.8±44.0 μg/dL; p<0.01), and transferrin saturation (TSAT; 25.9±12.7 vs. 38.8±15.7%; p<0.01), but by higher plasma level of the C-reactive protein (CRP; 7.0±6.7 vs. 1.2±1.3 mg/L; p<0.01). The obese women after 8 weeks of diet decreased their mean total body weight from 104.1±21.3 to 99.2±20.7 kg (p<0,0001). CRP level decreased slightly but significantly from 6.9±7.1 to 6.2±7.5 (p<0.05).
Conclusions. Obese women exhibit an increased level of CRP which may affect iron homeostasis. Weight loss leads to decrease in the CRP level, but it does not change haematologic parameters in the period of 8 weeks
DOI: 10.5604/12321966.1232092    
  FULL TEXT STATS

Recommend this article to:

Name:
E-mail:
From:
Language:


Related articles in IndexCopernicus™
     Iron [243 related records]
     Obesity [1444 related records]
     Women [628 related records]



 

Related articles

M Shah, Z Karena,
Treatment of Vaginal Atrophy with Vaginal Estrogen...
Objectives: To measure the effect of vaginal estrogen cream in the treatment of vaginal atrophy in menopausal Indian women. Methods: A total of 50 menopausal women aged between 40 and 80 years old with symptoms of vaginal atrophy were selected and tr...
ABSTRACT
O Ostroumova, A Kochetkov,
COMPARATIVE ANALYSIS OF THE EFFICACY OF FIXED-DOSE...
Aim. To study the characteristics of the daily profile of blood pressure (BP) and heart damage in patients with essential hypertension (HT), depending on the presence of obesity as well as the antihypertensive and organoprotective effects of fixed-do...
ABSTRACT
M Khodaveisi, A Omidi,
 The Effect of Pender’s Health Promotion Mo...
 Background: Changes in lifestyle and eating habits have put women at risk of obesity and overweight more than ever. This aim of this study was to investigate the effect of Pender’s Health Promotion Model (HPM) to improve the nutritional behav...
ABSTRACT