Parity does not affect diabetes complications in women with type 1 diabetes

Katarzyna Cypryk 1, Joanna Grycewicz 2, Patrycja Swierzewska 3, Marcin Kosinski 1, Andrzej Lewinski 4, Monika Zurawska-Klis 1
1 - Department of Diabetology and Metabolic Diseases, Medical University of Lodz, Poland
2 - Regional Centre of Occupational Medicine, Prevention and Treatment Centre in Lodz, Poland
3 - Outpatient Department of Diabetology in the Polish Mother’s Memorial Hospital/Research Institute in Lodz, Poland
4 - Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, Poland
Ann Agric Environ Med

ICID: 1230738
Article type: Original article
 
 
Abstract
Introduction.
The problem concerning the impact of pregnancy on diabetic complications is a matter for discussion as there is some evidence suggesting that pregnancy may trigger development or progression of diabetic chronic complications. However, currently available data concerning this issue is still controversial.
Objective. The aim of the study was to evaluate the impact of obstetric history on the development of chronic microangiopatic and macroangiopatic complications in type 1 diabetic women.
Materials and Method. The retrospective study comprised 226 white Caucasian type 1 diabetic women, including 190 parous and 36 nulliparous women. Anthropometric data, information concerning the course of the disease, including metabolic control and chronic complications, together with obstetric history, were registered.
Results. Parous women were older (p<0.001), but did not differ significantly regarding metabolic control in the course of the disease (p>0.05) and diabetes duration (p>0.05) from nulliparous subjects. There were no significant differences in the incidence (p>0.05) nor onset (p>0.05) of chronic diabetes complications between the groups. The number of deliveries did not correlate with either the incidence nor the onset of chronic complications. Longer DM duration at the moment of first delivery was related to the higher incidence of retinopathy (p<0.01), nephropathy (p<0.05) and neuropathy (p<0.001).
Conclusions. The incidence of chronic diabetic complications does not differ between parous women and the subjects that were never pregnant, and is not related to the number of pregnancies

DOI: 10.5604/12321966.1230738
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