The potential impact of the hypovitaminosis D on metabolic complications in obese adolescents – Preliminary results

Malgorzata Wojcik 1, Dominika Janus 1, Anna Kalicka-Kasperczyk 1, Krystyna Sztefko 2, Jerzy B. Starzyk 1
1 - Department of Pediatric and Adolescent Endocrinology, Chair of Pediatrics, Institute of Pediatrics, Jagiellonian University Medical College, Krakow, Poland
2 - Department of Clinical Biochemistry, Institute of Pediatrics, Jagiellonian University Medical College, Krakow, Poland
Ann Agric Environ Med

ICID: 1230676
Article type: Original article
 
 
Introduction and Objective. Vitamin D deficiency is common in obesity; however, its contribution in the development of metabolic complications remains uncertain. The aim of the study was to examine the relationships between vitamin D status and metabolic complications.
Materials and method. The results of blood pressure measurements, biochemical tests and ultrasound of the liver were compared in both groups. The study was conducted at the Children’s University Hospital in Krakow, Poland. 30 obese adolescents (mean 13.23y.o.); 18 with 25OHD levels <20ng/mL, 12 with 25OHD>20 ng/mL.
Results. The vitamin D deficient group presented with significantly higher values of the diastolic blood pressure (125.9vs.115mmHg), uric acid level (384.7vs.301.5umol/L) and lower phosphorus level (1.4vs.1.65mmol/L), higher prevalence of arterial hypertension (44vs.8.3%), and liver steatosis (25vs.8.3%); lower, but not significantly, levels of fibroblast growth factor 23 and fibroblast growth factor 19.
Conclusions. Hypovitaminosis D in obese adolescents is associated with higher prevalence of arterial hypertension, liver steatosis, elevated serum uric acid and low phosphorus levels. The potential contribution of the fibroblast growth factor 23 and fibroblast growth factor 19 in these complications development needs further investigation.

DOI: 10.5604/12321966.1230676
  FULL TEXT STATS

Recommend this article to:

Name:
E-mail:
From:
Language:


Related articles in IndexCopernicus™
     Obesity [1444 related records]
     Hypovitaminosis D [3 related records]
     Uric Acid [112 related records]
     arterial hypertension [417 related records]
     fibroblast growth factor 23 [2 related records]
     fibroblast growth factor 19 [0 related records]
     adolescents [531 related records]



 

Related articles

S Zanuso, M Bergamin,
Determination of metabolic equivalents during low-...
The purpose of this study was to quantify the metabolic equivalents (METs) of resistance exercise in obese patients with type 2 diabetes (T2DM) and healthy young subjects and to evaluate whether there were differences between sessions executed at low...
ABSTRACT
, ,
 EMOTIONAL MATURITY OF ADOLESCENTS IN RELATIO...
 Emotions do play central role in the life of an individual. One is expected to have higher emotional maturity in order to lead an effective life. It is also true that our behavior is constantly influenced by the emotional maturity level that ...
ABSTRACT
A Saidi , F Baba-Ahmed ,
Effect of Linseed Oil on Oxidative Stress Paramete...
The objective of this study was to determine linseed oil’s effect on oxidative stress parameters and lipid profile in three generations of offspring of obese rats. The initial age of the female rats is two months and of a weight of 100 ± 10 g w...
ABSTRACT