Impact of heavy metals on the female reproductive system

Piotr Rzymski 1, Katarzyna Tomczyk 2, Pawel Rzymski 2, Barbara Poniedziałek 1, Tomasz Opala 2, Maciej Wilczak 3
1 - Department of Biology and Environmental Protection, Poznan University of Medical Sciences, Poznan, Poland
2 - Department of Mother’s and Child’s Health, Poznan University of Medical Sciences, Poznan, Poland
3 - Department of Educational Medicine, Poznan University of Medical Sciences, Poznan, Poland
Ann Agric Environ Med
2015; 22 (2):
ICID: 1152077
Article type: Review article
Introduction. It has been recognized that environmental pollution can affect the quality of health of the human population. Heavy metals are among the group of highly emitted contaminants and their adverse effect of living organisms has been widely studied in recent decades. Lifestyle and quality of the ambient environment are among these factors which can mainly contribute to the heavy metals exposure in humans.
Objective. A review of literature linking heavy metals and the female reproductive system and description of the possible associations with emission and exposure of heavy metals and impairments of female reproductive system according to current knowledge.
Results. The potential health disorders caused by chronic or acute heavy metals toxicity include immunodeficiency, osteoporosis, neurodegeneration and organ failures. Potential linkages of heavy metals concentration found in different human organs and blood with oestrogen-dependent diseases such as breast cancer, endometrial cancer, endometriosis and spontaneous abortions, as well as pre-term deliveries, stillbirths and hypotrophy, have also been reported.
Conclusions. Environmental deterioration can lead to the elevated risk of human exposure to heavy metals, and consequently, health implications including disturbances in reproduction. It is therefore important to continue the investigations on metal-induced mechanisms of fertility impairment on the genetic, epigenetic and biochemical level.

DOI: 10.5604/12321966.1152077
PMID 26094520 - click here to show this article in PubMed

Recommend this article to:


Related articles in IndexCopernicus™
     Mercury [106 related records]
     Lead [265 related records]
     Cadmium [219 related records]
     Female reproductive system [2 related records]
     heavy metals [530 related records]


Related articles

M Samaei, M  Ehrampoush ,
Removal of Chromium and Cadmium from Wastewater in...
Background: Heavy metals have destructive and irreversible effects on the human, plants and animals. Some industries in Yazd enter industrial wastewater to municipal wastewater collection system. This can lead to high levels of heavy metals in wastew...
H Kamani, M Hoseini,
Factors affecting the concentrations of heavy meta...
Backgrounds and Objectives: Quantity of trace metals in the wet precipitation can illustrate the environmental pollution of different urban areas. Up to now, there is no study regarding the chemistry of wet precipitation in Tehran .The objectives of ...
A Vosoogh, M Saeedi,
River surface size fractioned sediments pollution ...
Introduction In recent years, restrictions of fresh water resources in the world and protection of the quality of these resources cause attention of many scientists about pollution of aquatic fresh waters like rivers. One of the most river pollutant...