The first evidence for vertical transmission of Babesia canis in a litter of Central Asian Shepherd dogs

Ewa J Mierzejewska 1, Renata Welc-Falęciak 1, Małgorzata Bednarska 1, Anna Rodo 2, Anna Bajer 1
1 - Department of Parasitology, Institute of Zoology, Faculty of Biology, University of Warsaw, Poland
2 - Department of Pathology and Veterinary Diagnostics, Warsaw University of Life Sciences – SGGW, Warsaw, Poland
Ann Agric Environ Med
2014; 21 (3):
ICID: 1120590
Article type: Original article
 
 
Introduction and objective. Tick-borne infections constitute an increasing health problem in dogs and may lead to death, especially in young or elderly individuals. Canine babesiosis constitutes a serious health problem in dogs worldwide. The aim of the study was to verify the probability of vertical transmission of Babesia canis between the bitch and the pups.
Materials and methods. In Autumn 2011, cases of babesiosis were diagnosed in a litter of 6-week-old puppies of a Central Asian Shepherd dog. Immediately following the first case of infection, blood samples were collected from all the pups in the litter (n=10) and from the female. Detection of Babesia infection was performed by molecular and microscopical techniques.
Results. The presence of B. canis DNA was detected using PCR in three pups, presenting at the time or 24–48 hours later with babesiosis symptoms, and in their asymptomatic mother. The isolates derived from the pups and the female – 520 bp 18S rRNA gene fragment – were compared and analyzed. All isolates from the pups and their mother were identical and showed 100% homology with B. canis group B (EU622793), supporting the same source of infection. Additionally, the USG of the peritoneal cavity was performed in the female, presenting evidence for splenomegaly.
Conclusions. On the basis of (1) the same timing of three pup cases; (2) the identical B. canis sequences derived from all positive dogs; (3) evident splenomegaly in the asymptomatic female, this provides the first evidence of the vertical transmission of this piroplasm in dogs.
DOI: 10.5604/12321966.1120590
PMID 25292117 - click here to show this article in PubMed
  FULL TEXT STATS

Recommend this article to:

Name:
E-mail:
From:
Language:


Related articles in IndexCopernicus™
     asymptomatic infections [0 related records]
     dog [70 related records]
     vertical transmission [11 related records]
     transplacental [0 related records]
     congenital [100 related records]
     Babesia canis [2 related records]



 

Related articles

M Safarpour, S Haghpanah,
Phenotype Report on Patients with Congenital Facto...
This study aimed to investigate clinical symptoms in patients with congenital factor V (FV) deficiency and the relationship between phenotype and factor activity level. Thirteen patients with congenital FV deficiency were investigated and the factor ...
ABSTRACT
,
 Inherited Posterior Paralysis in Crossbred P...
 Three cases of posterior paralysis were observed in T x D variety of crossbred piglets at ICAR Research institutes pig unit during last one year. Piglets were unable to move after birth but suckling colostrums with support. Average birth weig...
ABSTRACT
V K, J Vernekar,
 COMPARATIVE STUDY OF CT AND MRI IN EVALUATIO...
 BACKGROUND Suprahyoid neck encompasses the deep spaces between the base of skull and hyoid bone. The masses in the neck show a wide range of origin and can be congenital or acquired, inflammatory, vascular or neoplastic. Aim of the study is...
ABSTRACT